Deep learning enables fast, gentle STED microscopy

Deep learning enables fast, gentle STED microscopy

Blog Article

Abstract STED microscopy is widely used to image subcellular structures with super-resolution.Here, we report hot priest costume that restoring STED images with deep learning can mitigate photobleaching and photodamage by reducing the pixel dwell time by one or two orders of magnitude.Our method allows for efficient and robust restoration of noisy 2D and 3D STED images with multiple targets and facilitates long-term imaging ultrastar dc hc570 of mitochondrial dynamics.